Combined action of enzymes: the first domino reaction catalyzed by Agaricus bisporus

Publication Type
Journal contribution (peer reviewed)
Authors
Leutbecher, H.; Hajdok, S.; Braunberger, C.; Neumann, M.; Mika, S.; Conrad, J.; Beifuss, U.
Year of publication
2009
Published in
Green Chem.
Band/Volume
11/5
DOI
10.1039/B822977E
Page (from - to)
676-679
Abstract

The enzymes tyrosinase and laccase from a crude ext. of the button mushroom (Agaricus bisporus) can be employed to catalyze the domino reaction between phenol and various cyclic 1,3-dicarbonyls using atm. oxygen as the oxidizing agent and yielding annulated benzofuranes in a highly efficient and sustainable manner.

Involved persons

Involved institutions