Publications: Food Biofunctionality
| Title | Year | Literature Type | Authors |
|---|---|---|---|
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The long chain α–tocopherol metabolite α‐13’‐COOH and γ‐tocotrienol induce P‐glycoprotein expression and activity by activation of the pregnane X receptor in the intestinal cell line LS 180
Molecular Nutrition food research |
2017 | Journal contribution (peer reviewed) | Maren C. Podszun, Metta Jakobi, Marc Birringer, Johanna Weiss, Jan Frank |
| Transepithelial Transport of Curcumin in Caco-2 Cells Is significantly Enhanced by Micellar Solubilisation | 2017 | Journal contribution (peer reviewed) | Jan Frank, Christina Schiborr, Alexa Kocher, Jürgen Meins, Dariush Behnam, Manfred Schubert-Zsilavecz, Mona Abdel-Tawab |
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Effects of long-term Rice Bran Extract supplementation on survival, cognition and brain mitochondrial function in aged NMRI mice
NeuroMolecular Medicine |
2016 | Journal contribution (peer reviewed) | Hagl, S., Asseburg, H., Heinrich, M., Sus, N., Blumrich, E.-M., Dringen, R., Frank, J. & Eckert, G. P |
|
Effects of Long-Term Rice Bran Extract Supplementation on Survival, Cognition and Brain Mitochondrial Function in Aged NMRI Mice
NeuroMolecular Medicine |
2016 | Journal contribution (peer reviewed) | Stephanie Hagl, Heike Asseburg, Martina Heinrich, Nadine Sus, Eva-Maria Blumrich, Ralf Dringen, Jan Frank, Gunter P. Eckert |
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Highly bioavailable micellar curcuminoids accumulate in blood, are safe and do not reduce blood lipids and inflammation markers in moderately hyperlipidaemic individuals
Molecular Nutrition & Food Research |
2016 | Journal contribution (peer reviewed) | Alexa Kocher, Laura Bohnert, Christina Schiborr andJan Frank |
|
Intratumoral concentrations and effects of orally administered micellar curcuminoids in glioblastoma patients
Nutrition and Cancer |
2016 | Journal contribution (peer reviewed) | Dützmann, S., Schiborr, C., Kocher, A., Pilatus, U., Hattingen, E., Weissenberger, J., Gessler, F., Quick-Weller, J., Franz, K., Seifert, V., Frank, J. & Senft, C. |
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Intratumoral Concentrations and Effects of Orally Administered Micellar Curcuminoids in Glioblastoma Patients
Nutrition and Cancer |
2016 | Journal contribution (peer reviewed) | Stephan Dützmann, Christina Schiborr, Alexa Kocher, Ulrich Pilatus, Elke Hattingen, Jakob Weissenberger, Florian Geßler, Johanna Quick-Weller, Kea Frankz, Volker Seifert, Jan Frank & Christian Senft |
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Intratumoral Concentrations and Effects of Orally Administered Micellar Curcuminoids in Glioblastoma Patients
Nutrition and Cancer |
2016 | Journal contribution (peer reviewed) | Stephan Dützmann, Christina Schiborr, Alexa Kocher, Ulrich Pilatus, Elke Hattingen, Jakob Weissenberger, Florian Geßler, Johanna Quick-Weller, Kea Franz, Volker Seifert, Jan Frank & Christian Senft |
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Rice bran extract improves mitochondrial dysfunction in brains of aged NMRI mice
Nutritional Neuroscience |
2016 | Journal contribution (peer reviewed) | Stephanie Hagl*, Dirk Berressem, Rehka Grewal, Nadine Sus, Jan Frank & Gunter P. Eckert |
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The effect of conjugated linoleic acid supplements on oxidative and antioxidative status of dairy cows
Journal of Dairy Science |
2016 | Working paper | N.Hanschke, M.Kankofer, L.Ruda*M.Höltershinken, U.Meyer, J.Frank, S.Dänicke, J.Rehage |
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Beneficial Effects of Ethanolic and Hexanic Rice Bran Extract on Mitochondrial Function in PC12 Cells and the Search for Bioactive Components
Molecules |
2015 | Journal contribution (peer reviewed) | Stephanie Hagl, Dirk Berressem , Bastian Bruns , Nadine Sus, Jan Frank and Gunter P. Eckert |
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Concentrations of total curcuminoids in plasma, but not liver and kidney, are higher in 18- than in 3-months old mice
NFS Journal |
2015 | Journal contribution (peer reviewed) | Alexa Kocher, Stephanie Hagl, Christina Schiborr, Gunter P. Eckert, Jan Frank |
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Curcumin micelles improve mitochondrial function in neuronal PC12 cells and brains of NMRI mice – Impact on bioavailability
Neurochemistry International |
2015 | Journal contribution (peer reviewed) | Stephanie Hagl, Alexa Kocher, Christina Schiborr, Natalie Kolesova, Jan Frank, Gunter P. Eckert |
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Effects of curcumin in pediatric epithelial liver tumors: inhibition of tumor growth and alpha-fetoprotein in vitro and in vivo involving the NFkappaB- and the beta-catenin pathways
Impact Journals Oncotarget |
2015 | Journal contribution (peer reviewed) | Nicola Bortel, Sorin Armeanu-Ebinger, Evi Schmid, Bettina Kirchner, Jan Frank, Alexa Kocher, Christina Schiborr, Steven Warmann, Jörg Fuchs, Verena Ellerkamp |
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Non-targeted 1H-NMR-metabolomics suggest the induction of master regulators of energy metabolism in the liver of vitamin E-deficient rats
Food Funct. |
2015 | Journal contribution (peer reviewed) | Ali A. Moazzami,*a Sonja Frank,b Antonin Gombert Nadine Sus, Banu Bayram Gerald Rimbach, and Jan Frank |
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The oral bioavailability of curcuminoids in healthy humans is markedly enhanced by micellar solubilisation but not further improved by simultaneous ingestion of sesamin, ferulic acid, naringenin and xanthohumol
Journal of Functional Foods |
2015 | Journal contribution (peer reviewed) | Alexa Kochera, Christina Schiborra, Dariush Behnamb, Jan Frank |
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Tocopherols and tocotrienols in serum and liver of dairy cows receiving conjugated linoleic acids or a control fat supplement during early lactation
Journal of Dairy Science |
2015 | Working paper | H. Sadri, S. Dänicke, Ulrich Meyer, J. Rehage, J. Frank, H. Sauerwein |
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Adenosine triphosphate concentrations are higher in the brain of APOE3- compared to APOE4-targeted replacement mice and can be modulated by curcumin
Genes & Nutrition |
2014 | Journal contribution (peer reviewed) | Dawn Chin, Stephanie Hagl, Annika Hoehn, Patricia Huebbe, Kathrin Pallauf, Tilman Grune, Jan Frank, Gunter P. Eckert, Gerald Rimbach |
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Curcumin may impair iron status when fed to mice for six months
Redox Biology |
2014 | Working paper | Dawn Chin, Patricia Huebbea, Jan Frankb, Gerald Rimbacha, Kathrin Pallauf |
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CURCUMIN MICELLES IMPROVE MITOCHONDRIAL FUNCTION IN A MOUSE MODEL OF ALZHEIMER’S DISEASE
he Journal of Prevention of Alzheimer’s Disease |
2014 | Journal contribution (peer reviewed) | S. Hagl, M. Heinrich, A. Kocher, C. Schiborr, J. Frank, G.P. Eckert |
|
Dietary α-tocopherol and atorvastatin reduce high-fat-induced lipid accumulation and down-regulate CD36 protein in the liver of guinea pigs
The Journal of Nutritional Biochemistry |
2014 | Journal contribution (peer reviewed) | Maren C. Podszuna, Nadine Grebensteina, Astrid Sprussb, Thomas Schlueterc, Claus Kremoserc, Ina Bergheimb, Jan Frank |
| Dietary exposure to continuous small doses of α-cypermethrin in the presence or absence of dietary curcumin does not induce oxidative stress in male Wistar rats | 2014 | Journal contribution (peer reviewed) | Surat Hongsibsonga, b, Wolfgang Stuetz, b, c, Nadine Sus, Tippawan Prapamontol, Tilman Grune, Jan Frank |
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Rapid Method for Glutathione Quantitation Using High-Performance Liquid Chromatography with Coulometric Electrochemical Detection
J.Agric. food Chem |
2014 | Journal contribution (peer reviewed) | Banu Bayram, Gerald Rimbach, Jan Frank, Tuba Esatbeyoglu |
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The oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes
Molecular Nutrition & Food Research |
2014 | Journal contribution (peer reviewed) | Christina Schiborr, Alexa Kocher, Dariush Behnam, Josef Jandasek, Simone Toelstede andJan Frank |
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The use of total antioxidant capacity as surrogate marker for food quality and its effect on health is to be discouraged
Nutrition |
2014 | Journal contribution | Pompella A, Sies H, Wacker R, Brouns F, Grune T, Biesalski HK, Frank J |
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Vitamin E-drug interactions - molecular basis and clinical relevance.
Nutrition Research Reviews (NUTR RES REV) |
2014 | Other publication | Podszun, M. C. & Frank, J. |
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α-Tocopherol transfer protein is not required for the discrimination against γ-tocopherol in vivo but protects it from side-chain degradation in vitro
Mol Nutr Food Res |
2013 | Journal contribution | Grebenstein N, Schumacher M, Graeve L, Frank J |
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Isocitrate dehydrogenase 1 mutant R132H sensitizes glioma cells to BCNU- induced oxidative stress and cell death
Apoptosis |
2013 | Journal contribution | Mohrenz IV, Antonietti P, Pusch S, Capper D, Balss J, Voigt S, Weissert S, Mukrowsky A, Frank J, Senft C, Seifert V, vom Deimling A, Koegel D |
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Rice bran extract protects from mitochondrial dysfunction in guinea pig brains
Pharmacol Res |
2013 | Working paper | Hagl S, Kocher A, Schiborr C, Eckert S, Ciobanu I, Birringer M, El-Askary H, Helal A, Khayyal MT, Frank J, Müller WE, Eckert GP |
|
The oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes
Mol Nutr Food Res |
2013 | Journal contribution | Schiborr C, Behnam D, Jandasek J, Toelstede S, Frank J |
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The senescence-accelerated mouse - prone 8 is not a suitable model for the investigation of cardiac inflammation and oxidative stress and their modulation by dietary phytochemicals
Pharmacol Res |
2013 | Journal contribution | Schiborr C, Schwamm D, Kocher A, Rimbach G, Eckert GP, Frank J |
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Combination of PDT and inhibitor treatment affects melanoma cells and spares keratinocytes
Free Radic Biol Med |
2011 | Journal contribution | Kästle M, Grimm S, Nagel R, Breusing N, Grune T |
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The outcome of 5-ALA-mediated photodynamic treatment in melanoma cells is influenced by vitamin C and heme oxygenase-1
Biofactors |
2011 | Journal contribution | Grimm S, Mvondo D, Grune T, Breusing N |
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Effects of dietary phenolic compounds on tocopherol, cholesterol, and fatty acids in rats
Lipids |
2000 | Journal contribution | Kamal-Eldin A, Frank J, Razdan A, Tengblad S, Basu S, Vessby B |
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ATP-sensitive K+ channel modulator binding to sulphonylurea receptors SUR2A and SUR2B: Opposite effects of MgADP
Mol Pharmacol |
1999 | Journal contribution | Hambrock A, Löffler-Walz C, Kloor D, Delabar U, Horio Y, Kurachi Y, Quast U |
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Coexpression with the inward rectifier K+ channel Kir6.1 increases the affinity of the vascular sulfonylurea receptor SUR2B for glibenclamide
Mol Pharmacol |
1999 | Journal contribution | Russ U, Hambrock A, Artunc F, Löffler-Walz C, Horio Y, Kurachi Y, Quast U |
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Mg2+ and ATP dependence of KATP channel modulator binding to the recom¬binant sulphonylurea receptor, SUR2B
Br J Pharmacol |
1998 | Journal contribution | Hambrock A, Löffler-Walz C, Kurachi Y, Quast U |
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Binding and effects of KATP channel openers in the vascular smooth muscle cell line, A10
Br J Pharmacol |
1997 | Journal contribution | Russ U, Metzger F, Kickenweiz E, Hambrock A, Krippeit-Drews P, Quast U |