Isolation from Cussonia barteri of 1'-O-chlorogenoylchlorogenic acid and 1'-O-chlorogenoylneochlorogenic acid, a new type of quinic acid esters.

Publikations-Art

Zeitschriftenbeitrag

Autoren

Papajewski, S.; Vogler, B.; Conrad, J.; Klaiber, I.; Roos, G.; Walter, C. U.; Suessmuth, R.; Kraus, W.

Erscheinungsjahr

2001

Veröffentlicht in

Planta Med.

Band/Volume

67/8

Seite (von - bis)

732-736

1'-O-Chlorogenoylchlorogenic acid and 1'-O-chlorogenoylneochlorogenic acid, a new type of quinic acid esters, have been isolated, in addn. to six known quinic acid esters, rutin, and a mixt. of saponins, from the methanol ext. of Cussonia barteri Seemann (Araliaceae) leaves collected in Cameroon. Structure detn. was achieved by NMR, mass, IR, and UV spectroscopy. All compds. were tested for inhibitory activity on 5-lipoxygenase and cyclooxygenase-1, for antimicrobial activity against Bacillus subtilis, Pseudomonas fluorescens, and Cladosporium cucumerinum, and for haemolytic activity.