A new laccase-catalyzed domino process and its application to the efficient synthesis of 2-aryl-1H-benzimidazoles

Publikations-Art
Zeitschriftenbeitrag (peer-reviewed)
Autoren
Leutbecher, H.; Constantin, M.; Mika, S.; Conrad, J.; Beifuss, U.
Erscheinungsjahr
2011
Veröffentlicht in
Tetrahedron Lett.
Band/Volume
52/5
DOI
10.1016/j.tetlet.2010.11.145
Seite (von - bis)
605-608
Abstract

The laccase-catalyzed domino reaction of o-phenylenediamine and benzaldehydes with aerial oxygen as the oxidant exclusively yields 2-aryl-1H-benzimidazoles in good to very good yields. It is easy to perform under very mild reaction conditions.

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